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Pancreatitis, though rare, has been reported with GLP-1 receptor agonists including tirzepatide

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Limitations of This Comparison Several structural limitations constrain everything above, and honest readers should keep them in view: No head-to-head data

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Although kidney disease events have thus far been secondary outcomes in clinical trials, an ongoing phase III trial in patients with diabetic kidney disease will test the effect of a GLP1R agonist on a primary kidney disease outcome

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