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Hormonal and Structural Changes in Your 40s Skin changes become more noticeable in the 40s as a result of hormonal changes, especially in women due to the loss of estrogen

GLP-1 receptor agonists as a pharmacological class are well-studied

The rising prevalence of type 2 diabetes and obesity in these countries is increasing demand for effective GLP-1 agonist therapies

Gulyaeva NV (2023) Glucocorticoids Orchestrate Adult Hippocampal Plasticity: Growth Points and Translational Aspects

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Rodent studies showed that peripheral GLP-1 administration reduced alcohol intake in two-bottle free-choice models, that blocking GLP-1 receptors increased alcohol intake, and that direct injection into the ventral tegmental area was sufficient to reduce drinking