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The Schilling test distinguished PA from other forms of B 12 deficiency, [50] specifically, from ImerslundGrsbeck syndrome, a B 12 -deficiency caused by mutations in CUBN that codes for cubilin the cobalamin receptor

Finally, if the serum cobalamin concentration at the time of reevaluation is subnormal [lower than normal], further work-up is required to definitively diagnose the underlying disease process and cobalamin supplementation should be continued weekly or bi-weekly

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YES NO May be one of the cause, but if pain persists contact treating Physician

A full 12-week cycle typically uses two to three vials

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