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We conjecture that once established, such a proteopathy would no longer respond to B cell depletors (assuming these cells were the original source of the amyloidogenic seeds) after the cross-seeding event has taken hold

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doi:10.2460/javma.2000.217.650

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According to DelveInsights analysis, the United States represented approximately 60% of the total prevalent obesity cases in 2025 across the 7MM