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[2] [4] However, individual experiences vary considerablysome patients report minimal discomfort, whilst others may experience persistent symptoms requiring dose adjustment or additional management strategies

Jacques, E

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1 Introduction Post-exertional malaise (PEM) is characterized by a significant worsening of symptoms, such as fatigue and cognitive dysfunction, following mild physical, cognitive, or emotional exertion that the patient previously tolerated well

Pekala, Jolanta