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Afferent fibers from the trigeminal ganglion synapse on neurons in the trigeminal cervical complex (2), and ascending pathways transmit signals to various brain regions, causing pain, cutaneous allodynia, and sensory disturbances like photophobia and phonophobia (6, 34)

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While commonly found in foods of animal origin and fortified foods, many suffer from vitamin B-12 deficiency due to a low absorption rate or vegan diet