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In addition, the expression of THR- in the liver is inversely correlated with nonalcoholic fatty liver disease (NAFLD) activity score (NAS) 15

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Branded medications like Wegovy, Ozempic, Zepbound, and Mounjaro are FDA-approved for specific uses, such as chronic weight management or type 2 diabetes

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Building on clinical trial data demonstrating significant weight loss effects, the company pursued a separate indication specifically for chronic weight management