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Most customers report noticing a difference within two to four weeks of consistent daily use, with more pronounced results developing over 60 to 90 days

doi: 10.1038/ismej.2015.88 44 ClaessonMJCusackSOSullivanOGreene-DinizRde WeerdHFlanneryEet al

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However, more rigorous dataparticularly from well-controlled in vivo or translational researchis needed to clarify the extent and reliability of these effects

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reported fecal oxalate excretion to account for only 57% of the oxalate administered in rats treated with subcutaneously implanted minipumps [37]