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May 20, 2019

Understanding Alcohol's Impact on Your Body: Dehydration and Inflammation Alcohol acts as a diuretic, increasing urine production and potentially leading to significant dehydration, which contributes to headaches, fatigue, and dizziness

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10.3969/j.issn.1007-7669.2004.05.003 193 ZhouJ

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Phosphorylation of the DSGIS motif in NRF2 mediated by glycogen synthase kinase-3 beta (GSK-3) promotes the binding of -TrCP to NRF2 which is therefore marked for ubiquitination and then degraded by the proteasome [145, 149,150,151]