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This difference creates an inwardly directed electrical gradient as well as allowing for dramatic influxes of the ion in response to a variety of cellular stimuli

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longer-term durability beyond that timeframe remains under study

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It may be related to the dose of the toxic drug used or the period of study observation.However, most of the current research results support the antioxidant stress effect of GPX1, so GPX1 is an important antioxidant in mammals