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11 Modulation of invariant natural killer T (iNKT) cells by GLP-1RAs was another mechanism demonstrated to improve psoriasis

There was no improvement in fibrosis and hence results may be explained by weight loss rather than a direct result of semaglutide [100]

Weight loss plateaued around week 60

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Thus, future studies need to identify the genes responsible for GSH biosynthesis and the cellular mechanisms underlying the regulation of enzymes related to GSH metabolism or degradation