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Tesamorelin (2 mg/day) demonstrated reductions in trunk fat and visceral adipose tissue in HIVassociated lipodystrophy trials [3] [9]

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Biological Activity STS (Steroid sulfatase) inhibitor, with an IC of 25.8 nM

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2010s: Subcutaneous formulation and HSDD development Meanwhile, clinical development moved to a subcutaneous formulation and focused on acquired, generalized HSDD in premenopausal women