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membranaceus showed an increased percentage of Treg cells and a reduced percentage of Th17 cells, showing the capacity to modulate the balance of Treg/Th17 cells [70]

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It's a product with less skin irritation than well-known brightening functional ingredients and excellent melanin inhibition effect

We resolved disagreements on study selection and data extraction by consensus and discussion with all the authors/reviewers if required

Inclusion criteria included male sex, age between 18 and 60 yr, and body mass index (BMI) of 2035 kg/m 2

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