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Paul Wright, consultant cardiovascular pharmacist at Barts NHS Trust, commented: This is great news we saw a 20% risk reduction in major adverse coronary events in the SELECT trial, so [I am] keen to see how this can be offered to patients in practice

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Valproic acid and its metabolites can affect structures in the mitochondrial membrane 28,29 , and in rodent models the valproic acid impaired activity of cytochrome oxidase (cytochrome C) in the electron transport chain ( Figure 3 )

Blood Test (First Visit Only) A blood test is necessary before starting treatment to understand your initial body condition and treatment progress

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