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The most common side effects are mild and include injection site reactions (redness, slight swelling, or tenderness), mild headaches during the initial days of use, and occasional dizziness or lightheadedness

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qRT-PCR analysis revealed the marked upregulation of CDKN2A (encoding p16) , CDKN1A (encoding p21) , interleukin-8 ( IL-8) , and matrix metalloproteinase ( MMP)-12 expression (Figure 1D)

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UK pregnancy guidance advises limiting tuna to two steaks or four medium-sized cans per week, avoiding shark, swordfish and marlin completely, and limiting oily fish to two portions weekly