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Steril., 1984

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For semaglutide, the prescribing information says steady-state exposure is reached after four to five weeks of once-weekly dosing

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Front Biosci (Elite Ed)

Additionally, GA may inhibit 5-reductase and 3-hydroxysteroid dehydrogenase in the liver, slowing the degradation of aldosterone and affecting its metabolism (Latif et al., 1990