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The treatment, which was previously indicated only for symptomatic children 3 years of age and older with late infantile CLN2 disease, also known as Batten disease, can now be given to diagnosed children of all ages, regardless of whether they are symptomatic or presymptomatic

204 From a molecular biophysics perspective, neuromuscular control can be understood in terms of the biophysical processes that underlie muscle contraction and neuronal signaling

Additional risks include diabetic retinopathy complications (particularly with semaglutide in patients with pre-existing retinopathy), acute kidney injury (especially with volume depletion from gastrointestinal effects), and rare cases of intestinal obstruction or ileus

Both bypass the gut, so both produce strong serum levels

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Ribeiro-Parenti L, Jarry AC, Cavin JB, et al