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Both medications affect appetite through different mechanisms, which theoretically could enhance weight loss, but dual action also amplifies the risk of adverse interactions and overlapping side effects

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Gallbladder Problems: This can include gallstones or cholecystitis (inflammation of the gallbladder), leading to upper stomach pain, fever, yellowing of the skin or eyes (jaundice), or clay-colored stools

doi: 10.1016/s0300-483x(03)00188-4