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Interestingly, LDLR expression increased following inhibition of SREBP-2 or AMPK by siRNA, and also following treatment with thapsigargin, an endoplasmic reticulum stress inducer activating SREBP-2, or AICAR, an AMPK agonist

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M.CaoN.et al (2016)

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These medications are not indicated for type 1 diabetes or diabetic ketoacidosis (DKA)

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10.1073/pnas.1110085108 8 Brigelius-FlohR.MaurerS.LtzerK.BlG.KallionpH.LehtolainenP.et al

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Whole-cell patch-clamp recordings were performed on mRFP--actin-transfected hippocampal neurons to measure miniature excitatory postsynaptic currents (mEPSCs), reflecting synaptic activity [1]

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