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455 In addition, ferulic acid improves cognition dysfunction in copper-loaded Wilsons disease rats, suggesting that it reduces hippocampal neuron damage by activating SIRT1-mediated ferroptosis, providing a valuable drug candidate for the clinical treatment of cognitive impairment caused by Wilsons disease

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This action aids in regulating the neuroinflammatory response, which has the potential to decelerate the progression of the disease

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Reactivation of cAMP pathway by PDE4D inhibition represents a novel druggable Axis for overcoming tamoxifen resistance in ER-positive breast cancer