Am J Physiol Gastrointest Liver Physiol (2000) 279(3):G5616
The boost in energy and the feeling of reclaiming control over your health
Recommended For: Anyone with these concerns
This suggests that age may influence how sensory perception shifts during GLP-1 treatment
But there are scenarios where disclosure becomes relevant, and knowing how to handle those conversations is valuable preparation
Potential risks include: Enhanced gastrointestinal side effects (nausea, vomiting, diarrhea, constipation) Increased risk of nutritional deficiencies and protein malnutrition Potential worsening of gastroesophageal reflux symptoms Dehydration risk and acute kidney injury, particularly during dose escalation Increased risk of gallbladder disease and complications Risk of intestinal obstruction or ileus Diabetic retinopathy progression in patients with diabetes, particularly with rapid glycemic improvement Hypoglycemia risk, particularly in patients on insulin or sulfonylureas Cost considerations and insurance coverage challenges Rare but serious risks including pancreatitis and thyroid C-cell tumors (boxed warning) Clinicians must engage in shared decision-making with patients, carefully weighing these potential benefits against risks in the context of individual patient circumstances, surgical outcomes, comorbidities, and treatment goals
