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Storage temperature consistency Optimal: 2-8C (36-46F) constant Temperature fluctuations shorten shelf life: Frequent door opening warms vials temporarily Power outages or fridge malfunctions Storing in fridge door (warmest, most variable location) Best practice: Store in main fridge section (not door) Middle or back of shelf (most stable temperature) Away from freezer section (avoid freezing) Avoid frequent removal for extended periods Light exposure Peptides degrade faster with light exposure, especially UV light

Patients should discuss with their primary care physician and/or endocrinologist whether they should cease GLP-1 medication use in order to balance the risk of vision loss from NAION in the fellow eye with the hypoglycemic and cardiovascular benefits from treatment

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People who want body composition change, not just scale weight: since the peptide acts on fat metabolism, the relevant measure is body composition over time