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human risk unclear) Contraindications : GLP-1 medications should not be used by people with: Personal or family history of medullary thyroid carcinoma Multiple endocrine neoplasia syndrome type 2 History of pancreatitis Severe gastrointestinal disease Pregnancy or planning pregnancy Important Considerations for Perimenopausal Women Bone health : Some research suggests rapid weight loss may affect bone density

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Only 11.2% of participants discontinued due to side effects, meaning nearly 9 out of 10 people found it tolerable enough to continue

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