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Chromatographic conditions employ a C18 reversed-phase column, with acetonitrilewater solution (adjusted to an appropriate acidity with phosphoric acid) as the mobile phase

Some individuals also develop digestive symptoms, leading families to wonder, does B12 cause constipation? Vitamin B12 deficiency may slow normal digestive function in certain cases

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without the added step of bacteriostatic water for injection, theres an increased risk of microbial contamination

It also improves overall performance