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In obesity, the spontaneous (197, 198) and stimulated (199) pulsatile patterns of GH secretion governed by the hypothalamus are blunted, and the accumulation of abdominal adiposity, particularly visceral adipose tissue mass, was found to be a stronger negative determinant of GH secretion than other factors including age, sex, or generalized obesity (200202)

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This protection might be as a result of an ability of garlic components to inhibit phase 1 enzymes or induce phase 2 enzymes, GE antioxidant activity and/or its interaction with NAPQI to protect cellular GSH