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Understanding Semaglutide and Diet Semaglutide, commonly marketed under brand names like Ozempic and Wegovy, is a glucagon-like peptide-1 (GLP-1) receptor agonist that mimics a hormone in your body

He XH, Li WT, Peng WJ, Li GD, Wang SP, Xu LC

10 , 12 The delayed onset implies a gradual process of complex biopsychosocial adjustment rather than an acute drug reaction

As a result, the MACE event rate varied substantially for participants assigned to placebo, being greatest in EMPA-REG OUTCOME (43.9 per 1,000 patient-years), followed by CREDENCE (38.7 per 1,000 patient-years), CANVAS (31.5 per 1,000 patient-years), and finally DECLARE TIMI-58 (24.2 per 1,000 patient-years)

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Kidney injury may also occur in those without kidney disease, according to some reports