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In fact, this study shows that the levels of these molecules are significantly lower in joint fluid than in the blood/plasma and may be incidental to the function of the joints. Jeffrey Zarin, MD Also, there did not seem to be a difference between patients that had arthritis and those that did not, so conclusions about the effect of GLP-1 on arthritis should also be interpreted cautiously, Zarin added

They could also use lab valuesnot just HbA1c, but also lipids, glucose, liver function, and kidney functionto identify patients who are at high risk of cardiometabolic conditions and who might therefore benefit from GLP-1 drugs

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[12] It should be noted that in general, adequate thyroid replacement doses are needed to maintain normal lactation