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Nat Rev Drug Discov 19:673694 Smith RA, Miller TM, Yamanaka K et al (2006) Antisense oligonucleotide therapy for neurodegenerative disease

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The evidence isnt conclusive there are other factors at play but due to a lack of good safety information, Sebaratnam doesnt recommend using these sprays for cosmetic purposes

Safety and Considerations: Common side effects associated with these medications such as nausea, diarrhea, or changes in appetite

Therefore, beneficial effects of orally administered glutathione on exercise-induced fatigue 4 and liver function 5 cannot be explained simply by supplying glutathione or its precursors