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Dehydration from persistent nausea and vomiting can drop potassium and magnesium levels below normal ranges, leading to cramping and muscle weakness that feels similar to flu-like aches

In individuals with NOD2 mutations, the gut microbiota exhibits compositional and diversity dysregulation, characterized by a decreased abundance of certain beneficial bacteria and an excessive proliferation of harmful bacteria, which may exacerbate intestinal inflammatory responses

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It is known that insulin is involved in neuronal survival, synaptic plasticity, memory, and cognitive function in the central nervous system (CNS), and existing hypotheses suggest that similar to diabetic neuropathy, impaired insulin signalling pathways due to elevated blood glucose and lipids may be the main metabolic mechanism that induces the occurrence of diabetic cognitive dysfunction (6)