Cysteine is found in the lowest concentrations of the trio required to make GSH
The concentration of cytosolic and extracellular putrescine has been determined to be 22 nmol/g and 12 nmol/g , respectively [339]
The activation of cannabinoid CB1 receptors involves the inhibition of the activity of adenylate cyclase, with less production of the second messenger cAMP, initiates the closure of the Ca 2+ channels, inhibiting the entry of Ca 2+ ions, and opens the potassium channels causing hyperpolarisation of the membranes
Inoue A, Kikuchi S, Hishiki A et al (2014) A small molecule inhibitor of monoubiquitinated proliferating cell nuclear antigen (PCNA) inhibits repair of interstrand DNA cross-link, enhances DNA double strand break, and sensitizes cancer cells to cisplatin
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