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In short, there are a number of potential changes in the supply chain that are likely to reduce upward pressure on prices for semaglutide and GLP-1 medications in the years ahead, but that supply-side price relief may not come all at once and could even conceivably be outpaced and canceled out by upward price pressure due to growing demand

Meanwhile, just 2.8% of semaglutide users reported any levels of depression that required evaluation by a mental health professional during treatment compared with 4.1% of placebo users

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The three-phase mechanism works like this