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Starting estrogen-containing products, including oral contraceptives, may significantly decrease lamotrigine plasma levels, and stopping estrogen-containing oral contraceptives (including the pill-free week) may significantly increase lamotrigine plasma levels [see Warnings and Precautions (5.9), Clinical Pharmacology (12.3)]

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[DOI] [PubMed] [Google Scholar] 65.Bravo JF, Wolff C

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