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While these effects initially made GLP-1 seem a promising candidate for drug development, the earliest clinical studies from 1992 and 1993 revealed that GLP-1s half-life in the body was disappointingly short
However, how AMPK regulates GLP-1 signalling pathway needs to be further investigated
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For years, this left people choosing between uncomfortable injections or simply hoping their diet provided enough precursors to make their own
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Their therapeutic potential reinforces the continued value of natural products in developing new oncology treatments (70)
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