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An analogy I often use: its like pouring 10 gallons of gas into your car but only 1-2* gallons actually make it into the tank and power the engine, while the rest spills away - effective enough to drive, but inherently inefficient

Together, these advances reflect a growing emphasis on precision targeting of glial pathways and integrated neuro-immune modulation, paving the way for more effective and multifaceted treatment paradigms in PD

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They have rapid onsets, but the effects are typically short-lived due to the thyroid glands escape phenomenon (10)

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