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4.5 Antifungal drugs targeting iron transporters Iron is essential for fungal growth and pathogenicity, but the host limits its availability to prevent infection (Petrik et al., 2012
This indication is supported by the SURMOUNT clinical trial program, which demonstrated substantial and sustained weight reduction
aeruginosa strain lacking arachidonic acid-phosphatidylethanolamines (AA-PE) can convert AA-PE in host cells to 15-hydroperoxy-arachidonic acid-phosphatidylethanolamines (15-HOO-AA-PE) via its lipoxygenase (pLoxA), leading to lipid peroxidation and ferroptosis in human bronchial epithelial (HBE) cells during infection ( P
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Glucagon-like peptide-1 receptor activation in the ventral tegmental area decreases the reinforcing efficacy of cocaine
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