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Ministerio de Sanidad, Spain)

Reports also suggest that excessive clearance of ROS may be undesirable, possibly damaging specific essential intracellular signaling and metabolic functions and increasing susceptibility to infections [14]

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The consequent ROS accumulation in the body is inevitably associated with tissue injury [1], since ROS are known to damage cell components, particularly DNA, leading to loss of function, induction of apoptosis, or even carcinogenesis [2]