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These observations strongly suggest that estrogen deficiency causes bone loss by lowering thiol antioxidants in osteoclasts
GLP-1s can be taken alone or with other medications, including insulin, metformin, and SGLT-2 inhibitors
Retatrutide is becoming the focus for studies that require aggressive lipid clearance, extreme metabolic stabilization, or investigations into thermogenesis and energy balance
supports the bodys immune response
The severity and frequency of side effects vary
7 For patients with type 2 diabetes who have atherosclerotic cardiovascular disease or are at high risk for it or who have kidney disease or heart failure, either a GLP-1 receptor agonist or an SGLT-2 inhibitor with demonstrated cardiovascular benefit with or without metformin is recommended, independent of the hemoglobin A1c level (level of evidence A)
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