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Seminars Cancer Biol

Simon, Glutathione metabolism in cancer progression and treatment resistance

One outlier was excluded due to overcorrection for volume caused by a migration length of 1

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The thioredoxin system of mammalian cells and its modulators

As a central transcription factor, NRF2 influences this cell death mode by inducing a variety of genes including SLC7A11, GPX4, FSP1, NQO1, HMOX1, ferritin heavy chain 1 (FTH1), HECT and RLD domain-containing E3 ubiquitin protein ligase 2, and vesicle-associated membrane protein 8 in hepatocellular carcinoma and ovarian cancer cells [85, 86]