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Researchers analyzed health records from hundreds of thousands of people with diabetes

Large trials should be conducted to specifically study the effect of glucose-lowering therapy on dementia and cognitive decline, Dr

doi: 10.1016/j.jacl.2023.10.011

Preclinical work also points to applications in reproductive health (e.g., PCOS-related fertility improvements) and oncology, where observational studies link GLP-1 use to lower risks of obesity-related cancers

Therapeutic benefits to the cardiovascular and renal systems are emerging yet it currently remains unresolved if these are via direct actions on GLP-1R on these tissues or an indirect effect mediated by the health benefits of weight loss

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