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We chose a simple metricopening the Noom appbecause we know that once a member is engaged in the app, theyre likely to use one of the many tools weve developed to promote mindful eating, movement, and self-efficacy

Plasma levels of most acyl-carnitine species increased in response to carnitine supplementation, and the magnitude of these systemic increases was much greater than in tissues

That, in turn, can lead to further improvements downstream

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Patients with multiple comorbidities, polypharmacy, or metabolic complexity may benefit from in-depth clinical assessment before starting, particularly if genetic or biomarker data could inform dose selection and reduce adverse-event risk

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