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Treatment with MB at doses of 25 mg/kg and 50 mg/kg demonstrated dose-dependent hepatoprotective effects

Vitamin B12 and Weight Loss While Vitamin B12 itself doesnt cause weight loss, it helps the body convert fats and proteins into energy and aids in the breakdown of carbohydrates

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In BMAL1-knockout mice, pericytes progressively detach, extracellular matrix deposition is reduced, and tight junctions disassemble, leading to unstable neovasculature and loss of BBB integrity (79)

Estrogen can enhance autoimmune responses, which partly explains the female predominance of the disease