Br Med J 1(3248):553 Harvey CB, Bassett JD, Maruvada P, Yen PM, Williams GR (2007) The rat thyroid hormone receptor (TR) 3 displays cell-, TR isoform-, and thyroid hormone response element-specific actions
Considerations Slower onset: Because the peptide must traverse the nasal membranes and then enter general circulation (and eventually reach brain/central nervous system targets), the onset tends to be more gradual
However, taking excessively high doses without medical guidance or combining it with unsafe skin-lightening agents could result in side effects
Bertran-Alamillo J, Cattan V, Schoumacher M, Codony-Servat J, Gimnez-Capitn A, Cantero F, et al
Ding F, Ma B, Nazary-Vannani A, et al
Nongenomic roles of thyroid hormones and their derivatives in adult brain: are these compounds putative neurotransmitters