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The standard titration schedule of 4 weeks per dose level is a minimum, not a mandate

The injection is typically given in areas such as the abdomen, thigh, or upper arm, and can be done at home after proper instruction from a healthcare provider

Proper dose titration under clinical supervision significantly reduces tolerability issues

Preg test negative

The current understanding points to a potential biphasic pattern in GLP-1 RA studies, where any observed early worsening may be related to rapid glycemic improvement rather than direct retinal toxicity, particularly in patients with pre-existing retinopathy, poor glycemic control, and those undergoing HbA1c reduction 47