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Mechanistic insights from the REMODEL trial further support its role, identifying improvements in renal microvascular function through reduction of kidney fat, improved glomerular hemodynamics, attenuation of endothelial injury via metabolic reprogramming, and decreased inflammation and fibrosis
Fourteen reported subjective improvement, but there was no control group, no blinded assessment, no objective functional endpoint and no follow-up imaging endpoint [5]
PubMed Pickart, L., Vasquez-Soltero, J.M., & Margolina, A
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What are the common side effects compared to a full dose
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