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Wegovy injections contain water, two types of salt, and, in some cases, pH adjusters

Although the findings suggest that GLP-1 therapies may offer benefits beyond weight loss, liraglutide is the only GLP-1 receptor agonist evaluated in the clinic for migraine treatment

A meta-analysis of GLP-1RA CVOT showed that treatment with GLP-1RA reduced the risk of developing a composite kidney outcome including new-onset MA by 21% compared to placebo (HR 0.79, 95% CI 0.73-0.87), with only ELIXA and EXSCEL not achieving significant benefit [11]

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By working through multiple receptor systems, the mix may prevent or overcome compensatory mechanisms that limit single-peptide effect