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Introduction One of the incapacitating common neurological diseases is migraine which manifests in frequent attacks of headache and approximately 11% of the worldwide population suffer from this disorder (1)

Vitamin B12 and folate deficiency can cause a wide range of problems, including: extreme tiredness a lack of energy pins and needles (paraesthesia) a sore and red tongue mouth ulcers muscle weakness disturbed vision psychological problems, which may include depression and confusion problems with memory, understanding and judgement Some of these problems can also happen if you have a deficiency in vitamin B12 or folate but do not have anaemia

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Int J Pharm Pharm Sci 7(3):198202 Kowsalya S, Sudhaparimala S (2025) Nanoscale hydroxyapatite from marine and synthetic calcium sourcesfor efficient removal of p -chlorophenol

The first was substances with enough of a safety track record that the agency felt comfortable letting compounders use them while the final list was assembled