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Distinct gut microbiome characteristics and dynamics in patients with Parkinsons disease based on the presence of premotor rapid-eye movement sleep behavior disorders

Conclusion In sum, perturbation of Met metabolism may promote the damage process of hepatobiliary injury triggered by viral infections/toxins and/or niche abnormalities, with dysregulated inflammatory and immune responses of the liver, and contribute to the obliteration and eventual fibrosis and atresia of the bile ducts in the initiation/progression of BA

et al., 2023)

Soluble extracts were incubated with beads, and each sample was washed with PBS, pelleted, and analyzed with anti-Cop1 or anti-Pirh2 antibody