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Its measured by two numbers: Systolic (the first number): the pressure on your blood vessels when your heart pumps

Acknowledging these limitations is essential for contextualizing findings and guiding subsequent research toward rigorous, unbiased evaluation of GLP-1 RAs as gerotherapeutics within geroscience

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As one antioxidant enzyme, heme oxygenase-1 (HO-1) catalyzes heme to increase accumulation of ferrous iron, ROS production and lipid peroxidation, thereby triggers ferroptosis (Tang et al., 2025)

Typically, the initial effects of GLP-1 agonists on blood sugar control become apparent within the first week of treatment