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Ongoing Monitoring During Treatment Patients should be monitored at intervals that align with dose escalation schedules and clinical needs: During dose escalation : Assess for gastrointestinal side effects that may lead to dehydration, check blood pressure and heart rate, and evaluate tolerance

Plates were incubated for 15 min in a Spark 20M (Tecan) plate reader at 30 C and A 340nm was measured every 26 s with a 5 s shaking interval between measurements at 180 rpm using a 3 mm shaking diameter

The study was designed as proof of concept for NNMT as a drug-development target

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Though only currently indicated for diabetes, the combined HbA1c and weight loss benefits make Mounjaro a standout in the class, creating a level of demand that has significantly grown the size of the overall GLP-1 market

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