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Key findings include: Enhanced load-to-failure measurements in healing tendons compared to controls Improved collagen organization and fiber alignment at injury sites Accelerated tendon-to-bone healing in ligament injury models Dose-dependent effects with optimal responses observed at 10 mcg/kg in rodent studies TB-500 research demonstrated enhanced cellular migration and actin polymerization in tendon fibroblasts, while GHK-Cu studies showed increased collagen synthesis and improved tissue remodeling

[DOI] [PMC free article] [PubMed] [Google Scholar] 111.Schooneman M.G., Vaz F.M., Houten S.M., Soeters M.R

Copper is dangerous to cells on its own, but GHK carries it in safely and hands it off

Nat Rev Dis Primers (2019) 5:74